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This study demonstrates for the first time the ability to coat solid dispersions on microneedles as a means to deliver water‐insoluble drugs through the skin. Polyethylene glycol (PEG) was selected as the hydrophilic matrix, and lidocaine base was selected as the model hydrophobic drug to create the solid dispersion. First, thermal characterization and viscosity measurements of the PEG–lidocaine mixture...
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