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Dendritic cells are central orchestrators of the immune response. They communicate with both innate and adaptive immune systems and can aggravate or attenuate renal inflammation depending on the microenvironment and the stage of disease. This review summarizes current knowledge regarding the role of dendritic cells in renal inflammation and highlights the recent advances in understanding their function...
We previously found that dendritic cell (DC) precursors could be recruited into the peripheral blood of B6 mice by administration of macrophage inflammatory protein (MIP)-1α. These MIP-1α-recruited DCs could induce anti-tumor protective immunity when pulsed with tumor cell lysate. In this study, MIP-1α-recruited DCs could not effectively suppress preestablished tumor when pulsed with B16 tumor cell...
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