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Background The risk for osteoradionecrosis (ORN) of the mandible is positively related to bone volume exposed to > ~ 60 Gy. We hypothesized that in combined treatment, surgery may also be a risk factor. Patients and methods The impact of mandibular surgery on ORN in locally disease-free IMRT cohorts was retrospectively analyzed. Results Between October 2002 and October 2013, 531 of 715 patients...
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