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Oncoprotein p28GANK, overexpressed in hepatocellular carcinomas (HCC), binds to RelA and retains NF‐κB in the cytoplasm to suppress NF‐κB transactivation. However, the mechanism has not yet been elucidated. In this study, we clarified the mechanism of NF‐κB regulated by p28GANK. p28GANK reduced TNF‐α‐induced nuclear translocation of RelA/NF‐κB independent of HDAC3. p28GANK interacted with p300 to...
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