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Next‐Generation Tissue Engineering Heart Valves
In article number 2211267, Nianguo Dong, Weihua Qiao, and co‐workers report a newly‐constructed copper ion coated and GDF11 immobilized scaffold to successfully generate endogenous nitric oxide and improve hemocompatibility by down‐regulating platelets activation and adhesion, meanwhile significantly accelerating endothelialization through facilitating...
Tissue engineering heart valve (TEHV) offers great potential to overcome the limitations of commercial artificial valves used in clinical practice as a permanent prosthetic valve. Currently, decellularized heart valve (DHV) is the most widely used scaffold for TEHV, but showed suboptimal performance due to difficulty of endothelialization. Facilitating endothelialization of DHV is indispensable for...
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