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Background: In prostatic adenocarcinomas (PAs), the androgen up-regulates hypoxia inducible factor-1 alpha (HIF-1α). It has been reported that the regulation of HIF-1α would become a therapeutic strategy for PAs. This study was designed to elucidate whether or not HIF-1α expression would be associated with PA recurrence after neoadjuvant hormone therapy (NHT). Methods: The 50 radical prostatectomy...
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