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Abdominal aortic aneurysm is a serious vascular disease, which is the progressive dilation of the abdominal aorta caused by the weakening of the aortic wall. Its rupture has been known as a significant cause of mortality for adults older than sixty-five years of age. Screening and assessment of abdominal aortic aneurysms are currently performed by either ultrasound or computed tomography, with the...
The association of bone pathologies with atherosclerosis has stimulated the search for common mediators linking the skeletal and the vascular system. Since its initial discovery as a key regulator in bone metabolism, osteoprotegerin (OPG) has become the subject of intense interest for its role in vascular disease and calcification. Studies in vitro and in animal models suggest that OPG inhibits vascular...
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