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Chalcone derivatives have been synthesized by the reaction of 3-acetyl-2,5-dimethylthiophene with corresponding active aldehyde in ethanolic NaOH in microwave oven. The structure of these compounds was established by elemental analysis, IR, 1H NMR, 13C NMR and EI-MS spectral analysis. The anti-bacterial activity of these compounds were first tested in vitro by the disk diffusion assay against two...
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