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Background
The role of chemotherapy in extremity/trunk soft‐tissue sarcoma (ET‐STS) is controversial, even for patients at high risk for distant recurrence and death (those with high‐grade tumors ≥5 cm in size). This study examines the impact of integrating chemotherapy with neoadjuvant radiotherapy (RT) on overall survival (OS) for patients with high‐risk ET‐STS.
Methods
The National Cancer Data...
BACKGROUND
The addition of chemotherapy to adjuvant radiotherapy (chemotherapy and radiation therapy [CRT]) improves overall survival (OS) for patients with high‐risk grade 2 gliomas; however, the impact of chemotherapy alone (CA) is unknown. This study compares the OS of patients with high‐risk grade 2 gliomas treated with CA versus CRT.
METHODS
Patients with high‐risk grade 2 gliomas (subtotal...
BACKGROUND
Octogenarians and nonagenarians with stage II/III rectal adenocarcinomas are underrepresented in the randomized trials that have established the standard‐of‐care therapy of preoperative chemoradiation followed by definitive resection (ie, chemoradiation and then surgery [CRT+S]). The purpose of this study was to evaluate the impact of therapies on overall survival (OS) for patients with...
BACKGROUNDThe purpose of this study was to evaluate predictors of early distant brain failure (DBF) and salvage whole‐brain radiotherapy (WBRT) after treatment with stereotactic radiosurgery (SRS) for brain metastases and create a clinically relevant risk score to stratify patients’ risk for these events.
METHODSThe records of 270 patients with brain metastases who were treated with SRS between 2003...
BACKGROUNDThe patterns of lobar involvement, optimal treatment, and disease course among patients with gliomatosis cerebri (GC) have not been fully characterized. The current study evaluates the clinical presentations and outcomes for patients with GC treated with radiation therapy (RT) at our institution.
METHODSA total of 26 patients (25 with follow‐up) with GC were diagnosed and treated between...
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