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We evaluated the efficacy of treatment using reduced cumulative doses of anthracyclines in children with acute promyelocytic leukaemia (APL) in the Japanese Paediatric Leukaemia/Lymphoma Study Group AML‐P05 study. All patients received two and three subsequent courses of induction and consolidation chemotherapy respectively, consisting of all‐trans retinoic acid (ATRA), cytarabine and anthracyclines,...
To investigate the association between subjective sleep latency (sSL) fluctuation during the lead-in period and the placebo response in the subsequent double-blind period.The current study is a secondary analysis of data from the placebo arm (380 patients) of a double-blind study in outpatients with primary insomnia.Higher fluctuation of lead-in sSL was associated with a greater decrease in sSL in...
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