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The presence of low levels of functional human chorionic gonadotropin (hCG)/luteinizing hormone (LH) receptors in a number of nongonadal tissues of various species has recently been described. The rat mammary gland is one of the tissues that contains these receptors. This led us to the investigation of hCG/LH receptor expression in two breast cancer lines (MCF-7 and MDA MB 231) and in one normal...
The female reproductive system and bladder trigone are derived from intermediate mesoderm along the urogenital ridge during embryologic development. Since the female reproductive tract contains functional luteinizing hormone (LH)/human chorionic gonadotropin (hCG) receptors, we were interested in determining if these same receptors were also present in the bladder trigone. After obtaining informed...
Recently, the presence of luteinizing hormone (LH) / chorionic gonadotropin (hCG) receptors and the differentiation promoting effect of these hormones in the presence of estradiol (E) and progesterone (P) in human endometrial stromal cells have been described. Exogenous prostaglandin (PG)E 2 and the hormones that increase endogenous PGE 2 levels are also known to promote the differentiation...
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