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There are at least five murineDlxgenes that are related to theDrosophila Distal-lesshomeobox gene. TheDlxgenes are primarily expressed in the developing forebrain, derivatives of the cranial neural crest and restricted epidermal craniofacial and limb domains.Dlx-2is required for differentiation of subsets of cranial neural crest and forebrain cells. Previous genomic studies have shown thatDlx-1andDlx-2are...
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