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The significance of pericardial effects on diastolic function have not been investigated in relation to intraventricular pressure gradients and flow propagation. Previous investigations in an animal model have demonstrated the ability to noninvasively estimate diastolic intraventricular pressure gradients through application of the Euler equation to color Doppler M-mode echocardiographic data under...
Background: Heart failure due to diastolic dysfunction with preserved systolic function frequently occurs in hypertensive pts. However, mechanism of transition from compensated stage to isolated diastolic heart failure remains to be clarified.Methods: The study subjects consisted of Dahl salt sensitive rats fed with 8% NaCl since 7 wks old which develop hypertension and heart failure without systolic...
The purpose of the study was to investigate the relationship between noninvasive color M-mode flow propagation and pressure gradients, and invasive measured pressure changes in the left ventricle (LV) in an ischemic dog model.Methods: 5 open-chest anesthetized dogs were instrumented by a multi-sensor high fidelity catheter; one sensor in left atrium (LA), one at base and one at apex. Simultaneous...
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