Search results for: G. Corona

Items from 1 to 20 out of 87 results

article

European Academy of Andrology (EAA) guidelines on investigation, treatment and monitoring of functional hypogonadism in males

Giovanni Corona, Dimitrios G. Goulis, Ilpo Huhtaniemi, Michael Zitzmann, more

Andrology > 8 > 5 > 970 - 987

Background Evidence regarding functional hypogonadism, previously referred to as ‘late‐onset’ hypogonadism, has increased substantially during the last 10 year. Objective To update the European Academy of Andrology (EAA) guidelines on functional hypogonadism. Methods Expert group of academicians appointed by the EAA generated a series of consensus recommendations according to the GRADE (Grading...

article

EAA clinical practice guidelines—gynecomastia evaluation and management

G. A. Kanakis, L. Nordkap, A. K. Bang, A. E. Calogero, more

Andrology > 7 > 6 > 778 - 793

Background Gynecomastia (GM) is a benign proliferation of the glandular tissue of the breast in men. It is a frequent condition with a reported prevalence of 32–65%, depending on the age and the criteria used for definition. GM of infancy and puberty are common, benign conditions resolving spontaneously in the majority of cases. GM of adulthood is more prevalent among the elderly and proper investigation...

article

Clinical characteristics of men complaining of premature ejaculation together with erectile dysfunction: a cross‐sectional study

G. Rastrelli, S. Cipriani, G. Corona, L. Vignozzi, more

Andrology > 7 > 2 > 163 - 171

Background Premature ejaculation (PE) is present in up to 30% of men with erectile dysfunction (ED). Objectives To assess the clinical features of men complaining of both ED and PE (ED‐PE) as compared to men reporting only ED or PE. Materials and methods A consecutive series of 4024 men (mean age 51.2 ± 13.2 years) consulting for sexual dysfunction was studied. The population was categorized...

article

Genetics of ncHH: from a peculiar inheritance of a novel GNRHR mutation to a comprehensive review of the literature

F. Cioppi, A. Riera‐Escamilla, A. Manilall, E. Guarducci, more

Andrology > 7 > 1 > 88 - 101

Background Normosmic congenital hypogonadotropic hypogonadism (ncHH) is caused by the deficient production, secretion, or action of gonadotropin‐releasing hormone (GnRH). Its typical clinical manifestation is delayed puberty and azoospermia. Homozygous and compound heterozygous mutations in the GNRHR gene (4q13.2) are the most frequent genetic causes of ncHH. Objectives (i) Characterization at...

article

Testosterone deficiency in non-cancer opioid-treated patients

F. Coluzzi, D. Billeci, M. Maggi, G. Corona

Journal of Endocrinological Investigation > 2018 > 41 > 12 > 1377-1388

Purpose The use of opioids in patients with chronic non-cancer pain is common and can be associated with opioid-induced androgen deficiency (OPIAD) in men. This review aims to evaluate the current literature regarding the prevalence, clinical consequence and management of OPIAD. Methods A database search was performed in Medline, Embase and Cochrane using terms such as “analgesics”, “opioids” and...

article

P.01.13 METABOLOMICS AS COMPLEMENTARY OMIC APPROACH TO IMPLEMENT RISK CRITERIA FOR FIRST-DEGREE RELATIVES OF GASTRIC CANCER PATIENTS

V. De Re, G. Corona, M. De Zorzi, O. Repetto, more

Digestive and Liver Disease > 2018 > 50 > 2(S) > e124-e125

article

Approach to hyponatremia according to the clinical setting: Consensus statement from the Italian Society of Endocrinology (SIE), Italian Society of Nephrology (SIN), and Italian Association of Medical Oncology (AIOM)

E. Sbardella, A. M. Isidori, G. Arnaldi, M. Arosio, more

Journal of Endocrinological Investigation > 2018 > 41 > 1 > 3-19

E. Sbardella and A. M. Isidori contributed equally to this work.

article

Erectile function recovery in men treated with phosphodiesterase type 5 inhibitor administration after bilateral nerve‐sparing radical prostatectomy: a systematic review of placebo‐controlled randomized trials with trial sequential analysis

E. Limoncin, G. L. Gravina, G. Corona, M. Maggi, more

Andrology > 5 > 5 > 863 - 872

The impact of phosphodiesterase type 5 inhibitor (PDE5I) treatment modality (on‐demand vs. daily), PDE5I half‐life and time from surgery to PDE5I prescription on the achievement of drug‐assisted erectile function (EF) recovery is uncertain. We systematically reviewed published randomized clinical trials (RCTs). We performed meta‐analyses of data on 2317 men treated with PDE5Is after nerve‐sparing...

article

Sexual dysfunction in subjects treated with inhibitors of 5α‐reductase for benign prostatic hyperplasia: a comprehensive review and meta‐analysis

G. Corona, G. Tirabassi, D. Santi, E. Maseroli, more

Andrology > 5 > 4 > 671 - 678

Despite their efficacy in the treatment of benign prostatic hyperplasia, the popularity of inhibitors of 5α‐reductase (5ARIs) is limited by their association with adverse sexual side effects. The aim of this study was to review and meta‐analyze currently available randomized clinical trials evaluating the rate of sexual side effects in men treated with 5ARIs. An extensive Medline Embase and Cochrane...

article

The use of nutraceuticals in male sexual and reproductive disturbances: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS)

A. E. Calogero, A. Aversa, S. Vignera, G. Corona, more

Journal of Endocrinological Investigation > 2017 > 40 > 12 > 1389-1397

article

Field‐assisted paper spray mass spectrometry for therapeutic drug monitoring: 1. the case of imatinib in plasma

S. D'Aronco, M. Dall'Armi, S. Crotti, E. Calandra, more

Journal of Mass Spectrometry > 52 > 5 > 283 - 289

The field‐assisted paper spray (FAPS) – mass spectrometric method has been employed to quantify the imatinib (IMT) plasma levels in treated patients. The quantitative measurements have been performed on the collisionally generated fragment at m/z 394 of the protonated molecules of IMT and deuterated IMT (d₃‐IMT), used as internal standard. The FAPS‐tandem mass spectrometry (MS/MS) method exhibits...

article

The great opportunity of the andrological patient: cardiovascular and metabolic risk assessment and prevention

C. Foresta, A. Ferlin, A. Lenzi, P. Montorsi, more

Andrology > 5 > 3 > 408 - 413

Andrologists, cardiologists and diabetologists (and general practitioners) have the great opportunity to collaborate and find shared clinical workup for the benefit of a large number of men. Several evidence established a link between erectile dysfunction (ED), cardiovascular disease (CVD), diabetes, and metabolic syndrome. Not only these conditions share many risk factors and pathophysiological mechanisms...

article

Patient and caregiver goals for dementia care

Lee A. Jennings, Alina Palimaru, Maria G. Corona, Xavier E. Cagigas, more

Quality of Life Research > 2017 > 26 > 3 > 685-693

Purpose Most health outcome measures for chronic diseases do not incorporate specific health goals of patients and caregivers. To elicit patient-centered goals for dementia care, we conducted a qualitative study using focus groups of people with early-stage dementia and dementia caregivers. Methods We conducted 5 focus groups with 43 participants (7 with early-stage dementia and 36 caregivers);...

article

Evaluation of gene expression during 48 hours post-thawing in cryopreserved ovine fibroblasts

A. Idda, G. Corona, L. Masala, S. Ledda, more

Cryobiology > 2016 > 73 > 3 > 434

article

First‐generation phosphodiesterase type 5 inhibitors dropout: a comprehensive review and meta‐analysis

G. Corona, G. Rastrelli, A. Burri, E. Serra, more

Andrology > 4 > 6 > 1002 - 1009

The discontinuation rate with phosphodiesterase type 5 inhibitors (PDE5i) remains very high. The aim of this study was to review and meta‐analyze currently available data regarding dropout of the first‐generation of PDE5i including sildenafil, vardenafil, and tadalafil. An extensive Medline Embase and Cochrane search was performed including the following words: ‘PDE5i’, ‘discontinuation’. All observational...

article

MP35-03 LOWER URINARY TRACT SYMPTOMS AS RISK FACTOR FOR CARDIOVASCULAR EVENTS IN MEN: A SYSTEMATIC REVIEW AND META-ANALYSIS OF FIVE LONGITUDINAL TRIALS

M. Gacci, A. Sebastianelli, C. De Nunzio, S. Serni, more

The Journal of Urology > 2016 > 195 > 4(S) > e480

article

Testosterone supplementation and body composition: results from a meta-analysis of observational studies

G. Corona, V. A. Giagulli, E. Maseroli, L. Vignozzi, more

Journal of Endocrinological Investigation > 2016 > 39 > 9 > 967-981

Purpose The concept of testosterone (T) supplementation (TS) as a new anti-obesity medication in men with testosterone deficiency syndrome (TDS) is emerging. Data from placebo-controlled trials are more conflicting. The aim of this study is to systematically review and meta-analyze available observational and register studies reporting data on body composition in studies on TS in TDS. Methods An...

article

How to define hypogonadism? Results from a population of men consulting for sexual dysfunction

G. Rastrelli, G. Corona, M. Tarocchi, E. Mannucci, more

Journal of Endocrinological Investigation > 2016 > 39 > 4 > 473-484

Purpose The thresholds for testost erone (T) and the symptoms required for defining late onset hypogonadism (LOH) are under debate. The aims of the study are: (1) to verify the association between total and calculated free T (cfT) and sexual symptoms and (2) to identify thresholds for total and calculated free T to discriminate symptomatic from asymptomatic men. Methods A consecutive series of 4890...

article

Obesity and late-onset hypogonadism

G. Corona, L. Vignozzi, A. Sforza, E. Mannucci, more

Molecular and Cellular Endocrinology > 2015 > 418 > P2 > 120-133

Obesity and male hypogonadism (HG) are often associated, as demonstrated in all cross-sectional studies. Prospective studies have indicated that i) having HG at baseline increases the risk of visceral obesity (and metabolic syndrome) and that ii) obesity induces incident HG. Hence, there is a bidirectional relationship between the two conditions. This is the main topic of this review, along with some...

article

An integrated approach with vardenafil orodispersible tablet and cognitive behavioral sex therapy for treatment of erectile dysfunction: a randomized controlled pilot study

V. Boddi, G. Castellini, H. Casale, G. Rastrelli, more

Andrology > 3 > 5 > 909 - 918

Erectile Dysfunction is considered a multifactorial disease, where organic and psychological aspects are often interconnected. In a randomized controlled pilot study, we compared the efficacy of combined vardenafil orodispersible tablet (VARD) and cognitive‐behavioral sex therapy (CBST) vs. VARD alone in improving sexual symptoms in both male and female partners. Thirty male patients with erectile...

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Search results for: G. Corona

European Academy of Andrology (EAA) guidelines on investigation, treatment and monitoring of functional hypogonadism in males

EAA clinical practice guidelines—gynecomastia evaluation and management

Clinical characteristics of men complaining of premature ejaculation together with erectile dysfunction: a cross‐sectional study

Genetics of ncHH: from a peculiar inheritance of a novel GNRHR mutation to a comprehensive review of the literature

Testosterone deficiency in non-cancer opioid-treated patients

P.01.13 METABOLOMICS AS COMPLEMENTARY OMIC APPROACH TO IMPLEMENT RISK CRITERIA FOR FIRST-DEGREE RELATIVES OF GASTRIC CANCER PATIENTS

Approach to hyponatremia according to the clinical setting: Consensus statement from the Italian Society of Endocrinology (SIE), Italian Society of Nephrology (SIN), and Italian Association of Medical Oncology (AIOM)

Erectile function recovery in men treated with phosphodiesterase type 5 inhibitor administration after bilateral nerve‐sparing radical prostatectomy: a systematic review of placebo‐controlled randomized trials with trial sequential analysis

Sexual dysfunction in subjects treated with inhibitors of 5α‐reductase for benign prostatic hyperplasia: a comprehensive review and meta‐analysis

The use of nutraceuticals in male sexual and reproductive disturbances: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS)

Field‐assisted paper spray mass spectrometry for therapeutic drug monitoring: 1. the case of imatinib in plasma

The great opportunity of the andrological patient: cardiovascular and metabolic risk assessment and prevention

Patient and caregiver goals for dementia care

Evaluation of gene expression during 48 hours post-thawing in cryopreserved ovine fibroblasts

First‐generation phosphodiesterase type 5 inhibitors dropout: a comprehensive review and meta‐analysis

MP35-03 LOWER URINARY TRACT SYMPTOMS AS RISK FACTOR FOR CARDIOVASCULAR EVENTS IN MEN: A SYSTEMATIC REVIEW AND META-ANALYSIS OF FIVE LONGITUDINAL TRIALS

Testosterone supplementation and body composition: results from a meta-analysis of observational studies

How to define hypogonadism? Results from a population of men consulting for sexual dysfunction

Obesity and late-onset hypogonadism

An integrated approach with vardenafil orodispersible tablet and cognitive behavioral sex therapy for treatment of erectile dysfunction: a randomized controlled pilot study

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