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„Untreu“: Eine DNA‐abhängige DNA‐Polymerase, deren Wildtyp‐Vorläufer keine signifikante Reverse‐Transkriptase‐Aktivität zeigte, wurde beim Einbau eines Nukleotids gegenüber einem RNA‐Templat abgefangen und erstmals strukturell charakterisiert. Die signifikant erhöhte Reverse‐Transkriptase‐Aktivität der DNA‐ Polymerase‐Variante ermöglicht ihre Anwendung in PCR‐basierten molekular‐ diagnostischen Prozessen.
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