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Objective
Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis (RA). The phase III, 24‐month, placebo‐controlled Oral Rheumatoid Arthritis (ORAL) Scan trial was undertaken to evaluate the efficacy, including inhibition of structural progression, and safety of tofacitinib in patients with active RA and an inadequate response to methotrexate (MTX). Month 24 data from the completed...
The present study analyzes the frequency (prevalence rates) of vertebral pain syndrome (VPS) in 2844 women aged 40–89 years divided into groups based on the reproductive, perimenopausal and postmenopausal (PMP) stages of life and evaluates the relationship between the VPS rates and scores of bone mineral density (BMD). The overall VPS rates range from 84.1 to 94.4% throughout the different physiological...
Aim The aim of this study was to investigate the composition, stability, and biological activity of the complexes formed in solution upon interaction of calcium (Ca) ions with etidronic acid (EA), and to compare their effects on bone mineral density (BMD) in estrogen-deficient rats with osteoporosis. Materials and methods The study was conducted on 40 female Wistar rats. Osteoporosis was modeled...
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