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BACKGROUND
Anti‐E is the most common and important RBC alloantibody in the Chinese population. Several studies have demonstrated that the production of specific RBC alloantibodies is associated with HLA‐DRB1 polymorphisms. Considering that the Chinese population has its own unique characteristics of HLA‐DRB1 polymorphisms, we investigate whether specific HLA‐DRB1 alleles are associated with E immunization...
BACKGROUND
The para‐Bombay phenotype often results from a silenced β‐D‐galactoside 2‐α‐fucosyltransferase 1 (FUT1) gene (h/h) but an active FUT2 (Se/Se or Se/se) gene. We identified a para‐Bombay phenotype with two novel mutations in the FUT1 gene and homozygous mutated FUT2 (se357, 385/se357, 385) genes.
STUDY DESIGN AND METHODS
Red blood cell phenotype was detected by using a standard serologic...
BACKGROUND
Unexpected antibodies are frequently associated with hemolytic disease of the fetus and newborn (HDFN) and hemolytic transfusion reactions (HTRs), and screening for those unexpected antibodies is critical for the safety and effectiveness of transfusion. Different populations differ in the prevalence of significant antibodies and also the low‐frequency red blood cell (RBC) antigens. In...
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