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A novel fluorescent probe consisting of cobalt(II)/hydrogen peroxide–Amplex® UltraRed (Co2+/H2O2–AUR) for determining uric acid (UA) concentration is reported. In the presence of H2O2, Co2+ ions underwent oxidation to produce Co3+ ions and hydroxyl radicals, which then reacted with the fluorescence reagent, AUR, forming a fluorescence product at a pH of 9.0. If UA was present, it underwent oxidation...
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