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Assays to quantify myocardial renewal rely on the accurate identification of cardiomyocyte nuclei. We previously 14 C birth dated human cardiomyocytes based on the nuclear localization of cTroponins T and I. A recent report by Kajstura et al. suggested that cTroponin I is only localized to the nucleus in a senescent subpopulation of cardiomyocytes, implying that 14 C birth dating of...
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