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Three stable carcinoma cell lines, designated PLS10, PLS20 and PLS30, have been established from 3,2 -dimethyl-4-aminobiphenyl plus testosterone-induced carcinomas in the dorsolateral prostate of male F344 rats. The cells are keratin-positive and grow as typical epithelial monolayers in culture. When injected into intact male nude mice, PLS10 and PLS30 cells form well-differentiated adenocarcinomas...
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