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The aim of this study was to investigate the utility of three-dimensional (3D) high-frequency ultrasound in the longitudinally therapeutic evaluation of 188Re-human serum albumin microspheres (188Re-HSAM) in a GP7TB hepatoma model. Male F344 rats were intrahepatic inoculation with GP7TB 1 mm3 cubes. Studies were performed on rat at 26 days after tumor inoculation. The efficacy of 188Re-HSAM was performed...
The human serum albumin microsphere (HSA microsphere) is biodegradable and biocompatible, the SPECT/CT imaging and biodistribution of 188Re-HSA microspheres using new radio labeling process were investigated in a GP7TB hepatoma rat model. The labeling efficiency of the 188Re-HSA microspheres using new radio labeling process was about 97%. The levels of radioactivity within the liver peaked at 1 h...
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