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Both genetic and environmental factors contribute to rheumatoid arthritis (RA) as well as osteoarthritis (OA). For RA, most of the known genetic markers are linked with genes from immunological pathways. Recent genome‐wide association studies (GWAS) on RA identified known and novel susceptibility genes like HLA‐DRB1, PTPN22, STAT4, TRAF1/C5, OLIG3/TNFAIP3, CD40, CCL21, MMEL1‐TNFRSF14, CDK6, PRKCQ,...
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