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The activity of the synthetic somatostatin analogue SMS 201–995 was investigated in vitro on the growth of SW480 and SW620 human colon adenocarcinoma cell lines. The inhibition of cell proliferation was significant in SW480 cells (−19.6±1.4% at SMS 201–995 10 −9 m, P<0.05), but not in SW620 cells (−5.5±0.8% at SMS 201–995 10 −8 m) as compared to untreated cultures. Moreover, SMS...
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