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Alzheimer's is a neurodegenerative disease. Its symptoms are attributed to a deficiency of cholinergic neurotransmission. The drugs of choice for the treatment of Alzheimer's disease are acetylcholinesterase (AChE) inhibitors. Starting in the 1980's from non‐specific AChE inhibitors, the first‐generation drugs such as physostigmine, a second generation of more selective and better tolerated products...
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