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Progesterone (P) is secreted by the corpus luteum under the control of gonadotropin releasing hormone (GnRH)/luteinizing hormone (LH). Progesterone (P) is essential for reproduction because: (1) it induces in the endometrium the transcription of specific genes involved in the implantation of the blastocyst, (2) it modulates GnRH/LH secretion by decreasing GnRH pulse frequency, which in turn enriches...
Ovarian function is a continuous phenomenon in which the ovary has its own activity and local regulation, whereas the hypothalamo-pituitary axis controls and modulates the final steps of follicular growth and ovulation under the influence of the changing tide of ovarian signals (estradiol, progesterone, inhibins). Synchronized to follicular growth, ovulation, and corpus luteum function, the endometrium...
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