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Background:Mantle-cell lymphoma (MCL) is geneticallycharacterized by the translocation t(11;14)(q13;q32) leading to anoverexpression of cyclin-D1, but additional chromosomal abnormalities appearto be required for MCL pathogenesis. Patients and methods:Deletions involving chromosome 11q, whichwere recently found as recurrent aberrations in MCL, were analyzed at themolecular level in a series of 81...
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