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Purpose ApcMin/+ mouse is an excellent animal model bearing multiple intestinal neoplasia, used to simulate human familial adenomatous polyposis and colorectal tumors. The key point of this model is the mutation of Apc gene, which is a significant tumor-suppressor gene in the Wnt signaling pathway. There are also some other possible mechanisms responsible for the development of colorectal tumors in...
Although the theory of hypothesis testing is well developed and has a long history of application, practical application of hypothesis testing is plagued with fallacies, confusions, misconceptions, misuses, and abuses. This paper addresses four of the most widespread ones, particularly in statistical processing of signals, data, and information in uncertainty. They concern the decision on a single...
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