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The objective of this study was to determine the frequency of LOH at the NAT2 gene (chromosme 8p) in the Squamos cell carcinoma of the head and neck (HNSCC). In addition, we analysed if NAT2-LOH was related with several HNSCC clinical and pathological findings.Tumor and normal-DNA was obtained from 90 patients. The two most common NAT2-slow-acetylator polymorphisms (481 C>T and 590 A>G) were...
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