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The involvement of central nervous system (CNS) interleukin-1beta (IL-1β) in the pathogenesis of acute cardiac injury is still an unexplored issue. The present study was aimed to investigate whether cardiac injury could induce the activation of IL-1β in the spinal cord.Cardiac injury model in rats was established by intra-myocardial injection of formalin through the diaphragm. Western blot showed...
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