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Activation of phospholipases A 2 (PLA 2 s) leads to the generation of biologically active lipid mediators that can affect numerous cellular events. The Group VIA Ca 2+ -independent PLA 2 , designated iPLA 2 β, is active in the absence of Ca 2+ , activated by ATP, and inhibited by the bromoenol lactone suicide inhibitor (BEL). Over the past 10–15 years,...
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