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Quantitative acoustic microscopy (QAM) at 500 MHz permits measuring acoustic properties, such as speed of sound (SOS), attenuation (A) and acoustic impedance (Z), of tissue microstructure with a spatial resolution of 4 µm. Although high-frequency QAM has been shown to be a suitable tool for measuring the acoustic properties of several soft tissues, very few studies have been performed at 500 MHz,...
Because of time and cost constraints, current histological methods are unable to detect all clinically significant lymph-node metastases efficiently. Therefore, in previous studies, quantitative ultrasound (QUS) methods were developed to detect metastatic regions in freshly excised sentinel lymph nodes from breast-cancer patients using a 26-MHz transducer. A Gaussian form factor was used to obtain...
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