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Two techniques for inferring process outputs which can only be measured at infrequent intervals of time, from other more rapidly sampled secondary outputs, are proposed. Both estimators have quite general structures, the parameters of which can be updated on-line enabling the tracking of slow variations in both process and disturbance characteristics. The proposed methods require minimal design effort,...
It has long been thought that bioprocesses, with their inherent measurement difficulties and complex dynamics, posed almost insermountable problems to the control engineer. Although much research has recently been biased towards the development of biosensors to give more insight into process dynamics, this paper concentrates on more effective use of those measurements which are already available....
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