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It is well documented that Vitamin D 3 metabolites and synthetic analogs are metabolized to their epimers of the hydroxyl group at C-3 of the A-ring. We investigated the C-3 epimerization of Vitamin D 3 metabolites in various cultured cells and basic properties of the enzyme responsible for the C-3 epimerization. 1α,25-Dihydroxyvitamin D 3 [1α,25(OH) 2 D 3 ],...
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