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Ozonation of aqueous solutions of dimethylamine (DMA) leads to the formation of nitrosodimethylamine (NDMA). The yield of reaction is low (below 0.4% in relation to DMA) and increases with increasing pH. Contact time, ozone/DMA ratio and radical scavengers are other variables controlling the yield of reaction. Data from the literature and observed ozonation by-products suggest that nitrosation of...
Nitrosoamines, mainly N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA), are highly mutagenic compounds that are suspected of carcinogenic activity in the human body. The US Environmental Protection Agency (US EPA) classified these compounds into the B2 group, which indicates probable carcinogenicity to humans. According to the US EPA, the maximum admissible concentration of these compounds...
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