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Biomaterial nanotopographies have been proposed as a means to significantly influence cell functions (including osteoblasts, fibroblasts, endothelial cells, chondrocytes, immune cells, bacteria, etc.). In this study, vascular endothelial growth factor (VEGF) synthesis by breast adenocarcinoma cells on poly-lactic-co-glycolic acid (PLGA) films with various nanotopographies was investigated. Importantly,...
PLGA (poly-lactic-co-glycolic acid) has been widely used as a biomaterial in regenerative medicine due to its biocompatibility and biodegradability. The purpose of the present in vitro research was to prepare PLGA films with various nanometer surface features and determine whether lung cancer epithelial cells respond differently to such topographies. Different size polystyrene beads were used to cast...
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