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3,3′-Diindolylmethane is a dimer of indole-3-carbinol formed bothin vivoandin vitro.In this study, human cancer cells MCF-7 (with wild-type p53), T47-D (mutant p53), and Saos-2 (deficient in p53 gene), were used to examine the anticancer activities of 3,3′-diindolylmethane. The dose-dependent growth inhibitory effect was found in all these cell lines. Exposure of the cells to 50 μM solution of 3,3′-diindolylmethane...
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