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Reactive oxygen species (ROS)-responsive imaging systems could serve as probes for fluorescence detection at wound sites. In this study, curcumin-incorporated polymeric scaffolds were prepared, and their potential for the rapid detection of radical molecules as a wound stage marker was examined. Two types of nonwoven scaffolds, based on poly(lactic-co-glycolic) acid (PLGA)/poly(lactic acid) (PLA)...
Currently, the success of gene therapy is mainly limited due to the lack of effective vector systems. Although viral vectors are highly efficient in transfecting cells, undesirable complications limit their therapeutic applications. Chitosan has been investigated as a non-viral vector offering several advantages, such as biocompatibility, biodegradability and low toxicity with high cationic potential...
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