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•Newly diagnosed and recurrent high-grade gliomas, as well as low-grade gliomas, benefit from maximal safe resection.•The impact of EOR may vary on the basis of various molecular subtypes within both low- and high-grade gliomas.•We now have further insight into the impact of EOR based on MGMT status.•Because these findings are at odds with prior reports, more work focused on EOR and MGMT status is...
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