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Trisomies as sole cytogenetic abnormalities are extremely rare in acute lymphoblastic leukemia (ALL). We describe here the clinical features and immunophenotyping, cytogenetic, and fluorescence in situ hybridization (FISH) findings in a T-cell ALL patient with trisomy 4 as the sole cytogenetic abnormality. The leukemic clone was positive for CD2, CD7, CD34, and terminal deoxynucleotidyl transferase...
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