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In 2016, it is estimated 180,890 men are newly diagnosed with prostate cancer and 3,306,760 men live with prostate cancer in the United States. The introduction of multiparametric (mp) magnetic resonance imaging (MRI) of the prostate, standardised interpretation guidelines such as Prostate Imaging Reporting and Data System (PI-RADS version 2), and MRI-based targeted biopsy has improved detection of...
Introduction of urethral warmers to aid cryosurgery in the prostate has significantly reduced the incidence of urethral sloughing; however, the incidence rate still remains as high as 15%. Furthermore, urethral warmers have been associated with an increase of cancer recurrence rates. Here, we report results from our phantom-based investigation to determine the impact of a urethral warmer on temperature...
Tumor recurrence following percutaneous thermal ablation of hepatocellular carcinoma (HCC) remains a significant clinical problem, particularly in tumors ≥3.0cm. The aim of the present study was to test the hypothesis that sublethal heat stress of HCC cells or hepatocytes stimulates accelerated proliferation of non-heat stressed HCC cells and to identify candidate heat-stress induced pro-tumorigenic...
To assess the safety and efficacy of cryoablation in local tumor control for lung metastases ≤3.5 cm in patients with pulmonary metastatic disease.Twenty-two patients (13 males, 9 females; mean age 60 years) with up to 3 unilaterally or a maximum of 5 metastases bilaterally were enrolled in a prospective study and underwent CT guided cryoablation (Galil Medical, Arden Hills, MN). Patient Follow-up...
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