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The hypothalamus contains a number of nuclei that subserve a variety of functions, including generation of circadian rhythms, regulation of hormone secretion and maintenance of homeostatic levels for a variety of physiological parameters. Within the hypothalamus, γ‐amino‐butyric acid (GABA) is one of the major neurotransmitters responsible for cellular communication. Although GABA most commonly serves...
Background Increased secretion of oxytocin and arginine vasopressin (AVP) from hypothalamic magnocellular neurosecretory cells (MNCs) is a key physiological response to lactation. In the current study, we sought to test the hypothesis that the GABAA receptor-mediated inhibition of MNCs is altered in lactating rats. Results Gramicidin-perforated recordings in the rat supraoptic nucleus (SON) slices...
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