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The multiple sequence alignment of DNA or protein sequences is one of the fundamental research topics in bioinformatics. Kalign is an widely used multiple sequence alignment method employing the Wu-Manber approximate string matching algorithm, which improves both the accuracy and speed of multiple sequence alignment, and it is especially well suited for the task of aligning large numbers of sequences...
To elucidate biological functions from gene expression profiles, gene set enrichment analysis (GSEA) is widely applied against sets of predefined genes that may yield crucial clues to their functional themes or regulatory information. However, gene list derived from array based chromatin-immunoprecipitation (ChIP-chip) experiments, where all genes with one or more binding sites of a given protein,...
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