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The mechanism that estrogen (E 2 ) increases the number of endothelial progenitor cells (EPC) is largely unknown. Here we used E 2 -conjugated bovine serum albumin (E 2 -BSA, membrane impermeable) to investigate whether the membrane estrogen receptor (mER) and its related protein caveolin-1 (CAV-1) are involved in these processes.E 2 -BSA promoted [ 3 H]-thymidine...
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