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The discovery of an ever-expanding plethora of coding and non-coding RNAs with nodal and causal roles in the regulation of lung physiology and disease is reinvigorating interest in the clinical utility of the oligonucleotide therapeutic class. This is strongly supported through recent advances in nucleic acids chemistry, synthetic oligonucleotide delivery and viral gene therapy that have succeeded...
MicroRNAs (miRNAs) in blood can act as fingerprints to many diseases including cancer. However, detection of low levels of these miRNAs in blood demands for very sensitive techniques. Despite many reports available for miRNA detection, the available methodologies have drawbacks such as complexity, use of expensive enzymes, etc. We here report a new and simple electrochemical method to detect miRNAs...
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