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The level of expression of the various bioreductive enzymes which catalize the activation and detoxication of bioreductive antitumor agents has emerged as a new selective antitumor strategy. We examined the level of expression of DT-diaphorase (DTD), cyt. P450 reductase, cyt. b 5 reductase and alcohol dehydrogenase (ADH), within a panel of both animal and human tumor cell lines, and in some...
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