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We compared the effects of riboflavin pre-injection, co-injection and post-injection on several symptoms of zymosan-induced peritonitis in male Swiss mice. Additionally, the effects of i.p. injection of riboflavin itself were elucidated.Peritonitis was induced in Swiss mice (50 animals) by i.p. zymosan (Z; 40mg/kg) injection. Riboflavin (R; 0, 20, 50, or 100mg/kg) was applied either alone or in combination...
We investigated the effects of riboflavin (vitamin B2) on the kinetics of zymosan-induced peritonitis in three strains of mice.Peritonitis was induced in males of C57BL/6J, BALB/c and CBA mice by intraperitoneal injection of zymosan (40mg/kg) or zymosan supplemented with riboflavin (50mg/kg). During the first 45min of inflammation the pain symptoms were scored. At the selected time points (4, 6, 8,...
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