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Searching for novel antiobesity agents, a series of cannabinoid LH21 and of Rimonabant-fatty acid amide analogues have been prepared. Synthesis of pyrazoles 2a–2c was achieved by a two steps simple methodology via α,β-unsaturated ketones. Carboxamides 8a–8h were obtained in good yields from esters 7a–7c by a one-pot procedure which takes place under mild conditions. New compounds have been evaluated...
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