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p27 Kip1 (p27) is a member of the universal cyclin-dependent kinase inhibitor (CDKI) family and a putative tumor suppressor gene. In several tumors including lung cancer, decreased expression of p27 is associated with poor prognosis. These observations suggest a potential role for p27 as a new gene therapy target. In this study, we constructed adenovirus expressing human p27 (ad-p27) and investigated...
Let S be a semigroup whose set of proper right congruences form a tree. The main theorem is a characterization of those semigroups having this property. In this characterization we draw on the results of Schein and Tamura for commutative semigroups and Kozhukhov for left chain semigroups and Hitzel for nilpotent semigroups. The interested reader should also see the work of Nagy on Δ-semigroups.
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