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Background
Different populations of unipotent or multipotent stem cells have been identified in human epidermis and its appendages. It is well documented that these cells maintain tissue homeostasis and actively participate in epidermal regeneration after injury. However, there is no evidence of the presence of pluripotent stem cells in human epidermis.
Objectives
In this study we investigated...
Purpose
The goal of this study was to compare the cellular clonogenic response to proton beam and X‐ray irradiation of uveal melanoma cell line Mel270 and human melanoma cell line BLM.
Methods
BLM line was derived from a skin melanoma metastasis to the lung, and Mel270 is a primary uveal melanoma cell line. Cells were irradiated with 1–5 Gy of X ray (300 kVp Phillips, 1 Gy/min) or proton beam (60 MeV)...
Degradable aliphatic polyesters such as polylactides, polyglycolides and their copolymers are used in several biomedical and pharmaceutical applications. We analyzed the influence of poly(L-lactide-co-glycolide) (PLGA) thin films on the adhesion, proliferation, motility and differentiation of primary human skin keratinocytes and fibroblasts in the context of their potential use as cell carriers for...
The recently described method of cell electroporation by flow of cell suspension through localized direct current electric fields (dcEFs) was applied to identify non-toxic substances that could sensitize cells to external electric fields. We found that local cationic anesthetics such as procaine, lidocaine and tetracaine greatly facilitated the electroporation of AT2 rat prostate carcinoma cells and...
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