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Ca 2+ plays a complex role in the differentiation of committed pre-adipocytes into mature, fat laden adipocytes. Stim1 is a single pass transmembrane protein that has an essential role in regulating the influx of Ca 2+ ions through specific plasma membrane store-operated Ca 2+ channels. Stim1 is a sensor of endoplasmic reticulum Ca 2+ store content and when these stores...
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